EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.52 | acetyl-Leu-Leu-Nle-CHO | - |
Rattus norvegicus | |
3.4.22.52 | calpain inhibitor III | - |
Rattus norvegicus | |
3.4.22.52 | calpain inhibitor VI | - |
Rattus norvegicus | |
3.4.22.52 | calpeptin | - |
Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.52 | alpha-spectrin + H2O | Rattus norvegicus | - |
? | - |
? | |
3.4.22.52 | Na+/Ca2+ exchanger isoform 3 + H2O | Rattus norvegicus | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.52 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.52 | hippocampus | - |
Rattus norvegicus | - |
3.4.22.52 | neuron | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.52 | alpha-spectrin + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.4.22.52 | Na+/Ca2+ exchanger isoform 3 + H2O | - |
Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.52 | calpain 1 | - |
Rattus norvegicus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.4.22.52 | 0.0000075 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpain inhibitor VI | |
3.4.22.52 | 0.000008 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpain inhibitor III | |
3.4.22.52 | 0.000052 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpeptin | |
3.4.22.52 | 0.00019 | - |
pH and temperature not specified in the publication | Rattus norvegicus | acetyl-Leu-Leu-Nle-CHO |
EC Number | Organism | Comment | Expression |
---|---|---|---|
3.4.22.52 | Rattus norvegicus | MK801 added shortly after glutamate prevents calpain 1 activation | down |
3.4.22.52 | Rattus norvegicus | delayed calcium deregulation is not sufficient to activate calpain 1 | additional information |